3eoa: Difference between revisions

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==About this Structure==
==About this Structure==
[[3eoa]] is a 6 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EOA OCA].  
[[3eoa]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EOA OCA].  


==See Also==
==See Also==
*[[Integrin|Integrin]]
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[Monoclonal Antibody|Monoclonal Antibody]]



Revision as of 09:23, 20 October 2012

File:3eoa.png

Template:STRUCTURE 3eoa

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I

Template:ABSTRACT PUBMED 19258452

About this Structure

3eoa is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Li S, Wang H, Peng B, Zhang M, Zhang D, Hou S, Guo Y, Ding J. Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4349-54. Epub 2009 Mar 3. PMID:19258452

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