1c8k: Difference between revisions

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[[Image:1c8k.gif|left|200px]]<br /><applet load="1c8k" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1c8k.gif|left|200px]]
caption="1c8k, resolution 1.76&Aring;" />
 
'''FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE'''<br />
{{Structure
|PDB= 1c8k |SIZE=350|CAPTION= <scene name='initialview01'>1c8k</scene>, resolution 1.76&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene> and <scene name='pdbligand=CPB:2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE'>CPB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1]
|GENE=
}}
 
'''FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1C8K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=PLP:'>PLP</scene> and <scene name='pdbligand=CPB:'>CPB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8K OCA].  
1C8K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8K OCA].  


==Reference==
==Reference==
Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site., Oikonomakos NG, Schnier JB, Zographos SE, Skamnaki VT, Tsitsanou KE, Johnson LN, J Biol Chem. 2000 Nov 3;275(44):34566-73. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10924512 10924512]
Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site., Oikonomakos NG, Schnier JB, Zographos SE, Skamnaki VT, Tsitsanou KE, Johnson LN, J Biol Chem. 2000 Nov 3;275(44):34566-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10924512 10924512]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: transferase]]
[[Category: transferase]]


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