1c8t: Difference between revisions

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[[Image:1c8t.gif|left|200px]]<br /><applet load="1c8t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1c8t.gif|left|200px]]
caption="1c8t, resolution 2.60&Aring;" />
 
'''HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812'''<br />
{{Structure
|PDB= 1c8t |SIZE=350|CAPTION= <scene name='initialview01'>1c8t</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=TR1:2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER'>TR1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17]
|GENE=
}}
 
'''HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1C8T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=TR1:'>TR1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8T OCA].  
1C8T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8T OCA].  


==Reference==
==Reference==
Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1., Steele DL, El-Kabbani O, Dunten P, Windsor LJ, Kammlott RU, Crowther RL, Michoud C, Engler JA, Birktoft JJ, Protein Eng. 2000 Jun;13(6):397-405. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10877850 10877850]
Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1., Steele DL, El-Kabbani O, Dunten P, Windsor LJ, Kammlott RU, Crowther RL, Michoud C, Engler JA, Birktoft JJ, Protein Eng. 2000 Jun;13(6):397-405. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10877850 10877850]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein-inhibitor complex]]
[[Category: protein-inhibitor complex]]


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