1cet: Difference between revisions

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[[Image:1cet.jpg|left|200px]]<br /><applet load="1cet" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1cet.jpg|left|200px]]
caption="1cet, resolution 2.05&Aring;" />
 
'''CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE.'''<br />
{{Structure
|PDB= 1cet |SIZE=350|CAPTION= <scene name='initialview01'>1cet</scene>, resolution 2.05&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CLQ:N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE'>CLQ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]
|GENE=
}}
 
'''CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1CET is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=CLQ:'>CLQ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CET OCA].  
1CET is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CET OCA].  


==Reference==
==Reference==
Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase., Read JA, Wilkinson KW, Tranter R, Sessions RB, Brady RL, J Biol Chem. 1999 Apr 9;274(15):10213-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10187806 10187806]
Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase., Read JA, Wilkinson KW, Tranter R, Sessions RB, Brady RL, J Biol Chem. 1999 Apr 9;274(15):10213-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10187806 10187806]
[[Category: L-lactate dehydrogenase]]
[[Category: L-lactate dehydrogenase]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: tricarboxylic acid cycle]]
[[Category: tricarboxylic acid cycle]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:23:28 2008''
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