1cin: Difference between revisions

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[[Image:1cin.jpg|left|200px]]<br /><applet load="1cin" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1cin.jpg|left|200px]]
caption="1cin, resolution 2.1&Aring;" />
 
'''THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS'''<br />
{{Structure
|PDB= 1cin |SIZE=350|CAPTION= <scene name='initialview01'>1cin</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene> and <scene name='pdbligand=MTS:(4S-TRANS)-4-(METHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE'>MTS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1CIN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MMC:'>MMC</scene> and <scene name='pdbligand=MTS:'>MTS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CIN OCA].  
1CIN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CIN OCA].  


==Reference==
==Reference==
Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors., Smith GM, Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN, Protein Sci. 1994 Jan;3(1):118-25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8142888 8142888]
Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors., Smith GM, Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN, Protein Sci. 1994 Jan;3(1):118-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8142888 8142888]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: lyase(oxo-acid)]]
[[Category: lyase(oxo-acid)]]


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