3kme: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3kme]] is a 2 chain structure | [[3kme]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KME OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 10:22, 20 October 2012
Crystal structure of catalytic domain of TACE with phenyl-pyrrolidinyl-tartrate inhibitor
Template:ABSTRACT PUBMED 20022498
About this Structure
3kme is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rosner KE, Guo Z, Orth P, Shipps GW Jr, Belanger DB, Chan TY, Curran PJ, Dai C, Deng Y, Girijavallabhan VM, Hong L, Lavey BJ, Lee JF, Li D, Liu Z, Popovici-Muller J, Ting PC, Vaccaro H, Wang L, Wang T, Yu W, Zhou G, Niu X, Sun J, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Arshad Siddiqui M, Strickland CO. The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93. Epub 2009 Dec 5. PMID:20022498 doi:10.1016/j.bmcl.2009.12.004
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Categories:
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- ADAM 17 endopeptidase
- Homo sapiens
- Orth, P.
- A disintegrin and metalloproteinase domain 17
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Protease
- Snake venom-like protease
- Tnf-alpha convertase
- Tnf-alpha-converting enzyme
- Zymogen
