1csn: Difference between revisions
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[[Image:1csn.gif|left|200px]] | [[Image:1csn.gif|left|200px]] | ||
'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP''' | {{Structure | ||
|PDB= 1csn |SIZE=350|CAPTION= <scene name='initialview01'>1csn</scene>, resolution 2.0Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1CSN is a [ | 1CSN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSN OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:[http:// | Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7889932 7889932] | ||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: phosphotransferase]] | [[Category: phosphotransferase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:28:23 2008'' | ||
Revision as of 08:28, 20 March 2008
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| 1csn, resolution 2.0Å | |||||||||||||
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| Ligands: | MG, SO4 and ATP | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP
Overview
The structure of a truncated variant of casein kinase-1 from Schizosaccharomyces pombe, has been determined in complex with MgATP at 2.0 A resolution. The model resembles the 'closed', ATP-bound conformations of the cyclin-dependent kinase 2 and the cAMP-dependent protein kinase, with clear differences in the structure of surface loops that impart unique features to casein kinase-1. The structure is of unphosphorylated, active conformation of casein kinase-1 and the peptide-binding site is fully accessible to substrate.
About this Structure
1CSN is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.
Reference
Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:7889932
Page seeded by OCA on Thu Mar 20 10:28:23 2008
