1cy8: Difference between revisions

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[[Image:1cy8.gif|left|200px]]<br /><applet load="1cy8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1cy8.gif|left|200px]]
caption="1cy8, resolution 2.45&Aring;" />
 
'''COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'-THYMIDINE MONOPHOSPHATE AND 3'-THYMIDINE MONOPHOSPHATE'''<br />
{{Structure
|PDB= 1cy8 |SIZE=350|CAPTION= <scene name='initialview01'>1cy8</scene>, resolution 2.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=T3P:THYMIDINE-3'-PHOSPHATE'>T3P</scene> and <scene name='pdbligand=TMP:THYMIDINE-5'-PHOSPHATE'>TMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2]
|GENE=
}}
 
'''COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'-THYMIDINE MONOPHOSPHATE AND 3'-THYMIDINE MONOPHOSPHATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1CY8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=T3P:'>T3P</scene> and <scene name='pdbligand=TMP:'>TMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CY8 OCA].  
1CY8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CY8 OCA].  


==Reference==
==Reference==
Protein-nucleotide interactions in E. coli DNA topoisomerase I., Feinberg H, Changela A, Mondragon A, Nat Struct Biol. 1999 Oct;6(10):961-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10504732 10504732]
Protein-nucleotide interactions in E. coli DNA topoisomerase I., Feinberg H, Changela A, Mondragon A, Nat Struct Biol. 1999 Oct;6(10):961-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10504732 10504732]
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: relaxing enzyme]]
[[Category: relaxing enzyme]]


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