1czm: Difference between revisions

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[[Image:1czm.gif|left|200px]]~~<br /><applet load~~="1czm~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1czm.gif|left|200px]]

~~caption="~~1czm, resolution 2.0Å" />

'''DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I'''~~<br />~~

{{Structure

|PDB= 1czm |SIZE=350|CAPTION= <scene name='initialview01'>1czm</scene>, resolution 2.0Å

|SITE=

|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene> and <scene name='pdbligand=AAS:3-ACTOXYMERCURI-4-AMINOBENZENESULFONAMIDE'>AAS</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]

|GENE=

}}

'''DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I'''

==Overview==

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==About this Structure==

1CZM is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene> and <scene name='pdbligand=AAS:'>AAS</scene> as [http://en.wikipedia~~.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZM OCA].

1CZM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZM OCA].

==Reference==

Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme., Chakravarty S, Kannan KK, J Mol Biol. 1994 Oct 21;243(2):298-309. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~7932756 7932756]

Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme., Chakravarty S, Kannan KK, J Mol Biol. 1994 Oct 21;243(2):298-309. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7932756 7932756]

[[Category: Carbonate dehydratase]]

[[Category: Homo sapiens]]

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[[Category: ZN]]

[[Category: oxo-acid lyase]]

[[Category: protein-drug ~~interactions~~]]

[[Category: protein-drug interaction]]

[[Category: ~~sulfonamides~~]]

[[Category: sulfonamide]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 12~~:11:22 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:30:52 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1czm.gif|left|200px]]<br /><applet load="1czm" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1czm.gif|left|200px]]
-caption="1czm, resolution 2.0&Aring;" />
-'''DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I'''<br />
+ {{Structure
+|PDB= 1czm |SIZE=350|CAPTION= <scene name='initialview01'>1czm</scene>, resolution 2.0&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene> and <scene name='pdbligand=AAS:3-ACTOXYMERCURI-4-AMINOBENZENESULFONAMIDE'>AAS</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
+|GENE=
+}}
+'''DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-CZM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene> and <scene name='pdbligand=AAS:'>AAS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZM OCA].
+CZM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZM OCA].
 ==Reference==
-Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme., Chakravarty S, Kannan KK, J Mol Biol. 1994 Oct 21;243(2):298-309. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7932756 7932756]
+Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme., Chakravarty S, Kannan KK, J Mol Biol. 1994 Oct 21;243(2):298-309. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7932756 7932756]
 [[Category: Carbonate dehydratase]]
 [[Category: Homo sapiens]]
@@ Line 20: / Line 29: @@
 [[Category: ZN]]
 [[Category: oxo-acid lyase]]
-[[Category: protein-drug interactions]]
+[[Category: protein-drug interaction]]
-[[Category: sulfonamides]]
+[[Category: sulfonamide]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:11:22 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:30:52 2008''