1d1s: Difference between revisions

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[[Image:1d1s.gif|left|200px]]<br /><applet load="1d1s" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1d1s.gif|left|200px]]
caption="1d1s, resolution 2.5&Aring;" />
 
'''WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE'''<br />
{{Structure
|PDB= 1d1s |SIZE=350|CAPTION= <scene name='initialview01'>1d1s</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
|GENE=
}}
 
'''WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1D1S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=CAC:'>CAC</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1S OCA].  
1D1S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1S OCA].  


==Reference==
==Reference==
Methionine-141 directly influences the binding of 4-methylpyrazole in human sigma sigma alcohol dehydrogenase., Xie PT, Hurley TD, Protein Sci. 1999 Dec;8(12):2639-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10631979 10631979]
Methionine-141 directly influences the binding of 4-methylpyrazole in human sigma sigma alcohol dehydrogenase., Xie PT, Hurley TD, Protein Sci. 1999 Dec;8(12):2639-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10631979 10631979]
[[Category: Alcohol dehydrogenase]]
[[Category: Alcohol dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: rossman or dinucleotide fold]]
[[Category: rossman or dinucleotide fold]]


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