1d4i: Difference between revisions

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[[Image:1d4i.jpg|left|200px]]<br /><applet load="1d4i" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1d4i.jpg|left|200px]]
caption="1d4i, resolution 1.81&Aring;" />
 
'''HIV-1 protease in complex with the inhibitor BEA425'''<br />
{{Structure
|PDB= 1d4i |SIZE=350|CAPTION= <scene name='initialview01'>1d4i</scene>, resolution 1.81&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BEG:2,5-DIBENZYLOXY-3-HYDROXY-HEXANEDIOIC ACID BIS-[(2-HYDROXY-INDAN-1-YL)-AMIDE]'>BEG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE=
}}
 
'''HIV-1 protease in complex with the inhibitor BEA425'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1D4I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus] with <scene name='pdbligand=BEG:'>BEG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4I OCA].  
1D4I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4I OCA].  


==Reference==
==Reference==
Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors., Andersson HO, Fridborg K, Lowgren S, Alterman M, Muhlman A, Bjorsne M, Garg N, Kvarnstrom I, Schaal W, Classon B, Karlen A, Danielsson UH, Ahlsen G, Nillroth U, Vrang L, Oberg B, Samuelsson B, Hallberg A, Unge T, Eur J Biochem. 2003 Apr;270(8):1746-58. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12694187 12694187]
Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors., Andersson HO, Fridborg K, Lowgren S, Alterman M, Muhlman A, Bjorsne M, Garg N, Kvarnstrom I, Schaal W, Classon B, Karlen A, Danielsson UH, Ahlsen G, Nillroth U, Vrang L, Oberg B, Samuelsson B, Hallberg A, Unge T, Eur J Biochem. 2003 Apr;270(8):1746-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12694187 12694187]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus]]
[[Category: Human immunodeficiency virus]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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