1ra2: Difference between revisions

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==About this Structure==
==About this Structure==
[[1ra2]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA2 OCA].  
[[1ra2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA2 OCA].  


==See Also==
==See Also==

Revision as of 11:50, 20 October 2012

File:1ra2.png

Template:STRUCTURE 1ra2

DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)

Template:ABSTRACT PUBMED 9012674

About this Structure

1ra2 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 1997 Jan 21;36(3):586-603. PMID:9012674 doi:https://dx.doi.org/10.1021/bi962337c
  2. Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921

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