3n2v: Difference between revisions

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==About this Structure==
==About this Structure==
[[3n2v]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2V OCA].  
[[3n2v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2V OCA].  


==See Also==
==See Also==

Revision as of 12:10, 20 October 2012

File:3n2v.png

Template:STRUCTURE 3n2v

Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide

Template:ABSTRACT PUBMED 20965620

About this Structure

3n2v is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Attolino E, Calderone V, Dragoni E, Fragai M, Richichi B, Luchinat C, Nativi C. Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem. 2010 Oct 19. PMID:20965620 doi:10.1016/j.ejmech.2010.09.057
  2. Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z

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