1de9: Difference between revisions

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[[Image:1de9.gif|left|200px]]<br /><applet load="1de9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1de9.gif|left|200px]]
caption="1de9, resolution 3.0&Aring;" />
 
'''HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION'''<br />
{{Structure
|PDB= 1de9 |SIZE=350|CAPTION= <scene name='initialview01'>1de9</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE (II) ION'>MN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-(apurinic_or_apyrimidinic_site)_lyase DNA-(apurinic or apyrimidinic site) lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.99.18 4.2.99.18]
|GENE=
}}
 
'''HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DE9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MN:'>MN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA-(apurinic_or_apyrimidinic_site)_lyase DNA-(apurinic or apyrimidinic site) lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.99.18 4.2.99.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DE9 OCA].  
1DE9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DE9 OCA].  


==Reference==
==Reference==
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected], Mol CD, Izumi T, Mitra S, Tainer JA, Nature. 2000 Jan 27;403(6768):451-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10667800 10667800]
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected], Mol CD, Izumi T, Mitra S, Tainer JA, Nature. 2000 Jan 27;403(6768):451-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10667800 10667800]
[[Category: DNA-(apurinic or apyrimidinic site) lyase]]
[[Category: DNA-(apurinic or apyrimidinic site) lyase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: enzyme:dna complex]]
[[Category: enzyme:dna complex]]


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