1dr3: Difference between revisions

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[[Image:1dr3.gif|left|200px]]<br /><applet load="1dr3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dr3.gif|left|200px]]
caption="1dr3, resolution 2.3&Aring;" />
 
'''2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN'''<br />
{{Structure
|PDB= 1dr3 |SIZE=350|CAPTION= <scene name='initialview01'>1dr3</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TAP:7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>TAP</scene> and <scene name='pdbligand=HBI:7,8-DIHYDROBIOPTERIN'>HBI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
|GENE=
}}
 
'''2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DR3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=TAP:'>TAP</scene> and <scene name='pdbligand=HBI:'>HBI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DR3 OCA].  
1DR3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DR3 OCA].  


==Reference==
==Reference==
Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes., McTigue MA, Davies JF 2nd, Kaufman BT, Kraut J, Biochemistry. 1993 Jul 13;32(27):6855-62. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8334118 8334118]
Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes., McTigue MA, Davies JF 2nd, Kaufman BT, Kraut J, Biochemistry. 1993 Jul 13;32(27):6855-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8334118 8334118]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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