1drf: Difference between revisions

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[[Image:1drf.gif|left|200px]]<br /><applet load="1drf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1drf.gif|left|200px]]
caption="1drf, resolution 2.0&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE'''<br />
{{Structure
|PDB= 1drf |SIZE=350|CAPTION= <scene name='initialview01'>1drf</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=FOL:FOLIC ACID'>FOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DRF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=FOL:'>FOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DRF OCA].  
1DRF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DRF OCA].  


==Reference==
==Reference==
Crystal structure of human dihydrofolate reductase complexed with folate., Oefner C, D'Arcy A, Winkler FK, Eur J Biochem. 1988 Jun 1;174(2):377-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3383852 3383852]
Crystal structure of human dihydrofolate reductase complexed with folate., Oefner C, D'Arcy A, Winkler FK, Eur J Biochem. 1988 Jun 1;174(2):377-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3383852 3383852]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: oxidoreductase (ch-nh(d)-nad or nadp(a))]]
[[Category: oxidoreductase (ch-nh(d)-nad or nadp(a))]]


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