1dtg: Difference between revisions

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[[Image:1dtg.gif|left|200px]]<br /><applet load="1dtg" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dtg.gif|left|200px]]
caption="1dtg, resolution 2.4&Aring;" />
 
'''HUMAN TRANSFERRIN N-LOBE MUTANT H249E'''<br />
{{Structure
|PDB= 1dtg |SIZE=350|CAPTION= <scene name='initialview01'>1dtg</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=CO3:CARBONATE ION'>CO3</scene>
|ACTIVITY=
|GENE=
}}
 
'''HUMAN TRANSFERRIN N-LOBE MUTANT H249E'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DTG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE:'>FE</scene> and <scene name='pdbligand=CO3:'>CO3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTG OCA].  
1DTG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTG OCA].  


==Reference==
==Reference==
Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release., MacGillivray RT, Bewley MC, Smith CA, He QY, Mason AB, Woodworth RC, Baker EN, Biochemistry. 2000 Feb 15;39(6):1211-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10684598 10684598]
Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release., MacGillivray RT, Bewley MC, Smith CA, He QY, Mason AB, Woodworth RC, Baker EN, Biochemistry. 2000 Feb 15;39(6):1211-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10684598 10684598]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: signal]]
[[Category: signal]]


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