1dtt: Difference between revisions

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[[Image:1dtt.gif|left|200px]]~~<br /><applet load~~="1dtt~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1dtt.gif|left|200px]]

~~caption="~~1dtt, resolution 3.0Å" />

'''CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)'''~~<br />~~

{{Structure

|PDB= 1dtt |SIZE=350|CAPTION= <scene name='initialview01'>1dtt</scene>, resolution 3.0Å

|SITE=

|LIGAND= <scene name='pdbligand=FTC:N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA'>FTC</scene>

|ACTIVITY=

|GENE=

}}

'''CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)'''

==Overview==

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==About this Structure==

1DTT is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1~~] with <scene name='pdbligand=FTC:'>FTC</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTT OCA].

1DTT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTT OCA].

==Reference==

Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses., Ren J, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S, Slater M, Milton J, Balzarini J, Stuart DI, Stammers DK, J Biol Chem. 2000 Feb 25;275(8):5633-9. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~10681546 10681546]

Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses., Ren J, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S, Slater M, Milton J, Balzarini J, Stuart DI, Stammers DK, J Biol Chem. 2000 Feb 25;275(8):5633-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10681546 10681546]

[[Category: Human immunodeficiency virus 1]]

[[Category: Protein complex]]

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[[Category: FTC]]

[[Category: drug design]]

[[Category: hiv-1 reverse transcriptase ~~aids~~]]

[[Category: hiv-1 reverse transcriptase aid]]

[[Category: non-nucleoside inhibitor]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 12~~:20:21 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:44:11 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1dtt.gif|left|200px]]<br /><applet load="1dtt" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1dtt.gif|left|200px]]
-caption="1dtt, resolution 3.0&Aring;" />
-'''CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)'''<br />
+ {{Structure
+|PDB= 1dtt |SIZE=350|CAPTION= <scene name='initialview01'>1dtt</scene>, resolution 3.0&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=FTC:N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA'>FTC</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-DTT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=FTC:'>FTC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTT OCA].
+DTT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTT OCA].
 ==Reference==
-Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses., Ren J, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S, Slater M, Milton J, Balzarini J, Stuart DI, Stammers DK, J Biol Chem. 2000 Feb 25;275(8):5633-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10681546 10681546]
+Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses., Ren J, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S, Slater M, Milton J, Balzarini J, Stuart DI, Stammers DK, J Biol Chem. 2000 Feb 25;275(8):5633-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10681546 10681546]
 [[Category: Human immunodeficiency virus 1]]
 [[Category: Protein complex]]
@@ Line 26: / Line 35: @@
 [[Category: FTC]]
 [[Category: drug design]]
-[[Category: hiv-1 reverse transcriptase aids]]
+[[Category: hiv-1 reverse transcriptase aid]]
 [[Category: non-nucleoside inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:20:21 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:44:11 2008''