3o5n: Difference between revisions

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==About this Structure==
==About this Structure==
[[3o5n]] is a 8 chain structure of [[Shank protein]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA].  
[[3o5n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA].  


==See Also==
==See Also==

Revision as of 13:24, 20 October 2012

File:3o5n.png

Template:STRUCTURE 3o5n

Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders

Template:ABSTRACT PUBMED 21626699

About this Structure

3o5n is a 8 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Saupe J, Roske Y, Schillinger C, Kamdem N, Radetzki S, Diehl A, Oschkinat H, Krause G, Heinemann U, Rademann J. Discovery, Structure-Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain. ChemMedChem. 2011 May 27. doi: 10.1002/cmdc.201100094. PMID:21626699 doi:10.1002/cmdc.201100094

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