1e2m: Difference between revisions

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[[Image:1e2m.gif|left|200px]]<br /><applet load="1e2m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1e2m.gif|left|200px]]
caption="1e2m, resolution 2.2&Aring;" />
 
'''HPT + HMTT'''<br />
{{Structure
|PDB= 1e2m |SIZE=350|CAPTION= <scene name='initialview01'>1e2m</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=HPT:6-HYDROXYPROPYLTHYMINE'>HPT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21]
|GENE=
}}
 
'''HPT + HMTT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1E2M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=HPT:'>HPT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2M OCA].  
1E2M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2M OCA].  


==Reference==
==Reference==
The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase., Wurth C, Kessler U, Vogt J, Schulz GE, Folkers G, Scapozza L, Protein Sci. 2001 Jan;10(1):63-73. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11266595 11266595]
The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase., Wurth C, Kessler U, Vogt J, Schulz GE, Folkers G, Scapozza L, Protein Sci. 2001 Jan;10(1):63-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11266595 11266595]
[[Category: Human herpesvirus 4]]
[[Category: Human herpesvirus 4]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: null]]
[[Category: null]]


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