1e4e: Difference between revisions

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[[Image:1e4e.jpg|left|200px]]<br /><applet load="1e4e" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1e4e.jpg|left|200px]]
caption="1e4e, resolution 2.5&Aring;" />
 
'''D-ALANYL-D-LACATE LIGASE'''<br />
{{Structure
|PDB= 1e4e |SIZE=350|CAPTION= <scene name='initialview01'>1e4e</scene>, resolution 2.5&Aring;
|SITE= <scene name='pdbsite=AC1:Phy+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Phy+Binding+Site+For+Chain+B'>AC2</scene>, <scene name='pdbsite=AC3:Adp+Binding+Site+For+Chain+A'>AC3</scene> and <scene name='pdbsite=AC4:Adp+Binding+Site+For+Chain+B'>AC4</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PHY:1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC+ACID'>PHY</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= VANA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1352 Enterococcus faecium])
}}
 
'''D-ALANYL-D-LACATE LIGASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1E4E is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ADP:'>ADP</scene>, <scene name='pdbligand=PHY:'>PHY</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Phy+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Phy+Binding+Site+For+Chain+B'>AC2</scene>, <scene name='pdbsite=AC3:Adp+Binding+Site+For+Chain+A'>AC3</scene> and <scene name='pdbsite=AC4:Adp+Binding+Site+For+Chain+B'>AC4</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4E OCA].  
1E4E is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4E OCA].  


==Reference==
==Reference==
The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of D-alanyl-D-lactate ligase (VanA)., Roper DI, Huyton T, Vagin A, Dodson G, Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8921-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10908650 10908650]
The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of D-alanyl-D-lactate ligase (VanA)., Roper DI, Huyton T, Vagin A, Dodson G, Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8921-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10908650 10908650]
[[Category: Enterococcus faecium]]
[[Category: Enterococcus faecium]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: plasmid]]
[[Category: plasmid]]


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