2y7x: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2y7x]] is a 2 chain structure | [[2y7x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7X OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 14:04, 20 October 2012
THE DISCOVERY OF POTENT AND LONG-ACTING ORAL FACTOR XA INHIBITORS WITH TETRAHYDROISOQUINOLINE AND BENZAZEPINE P4 MOTIFS
Template:ABSTRACT PUBMED 21349711
About this Structure
2y7x is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Watson NS, Adams C, Belton D, Brown D, Burns-Kurtis CL, Chaudry L, Chan C, Convery MA, Davies DE, Exall AM, Harling JD, Irvine S, Irving WR, Kleanthous S, McLay IM, Pateman AJ, Patikis AN, Roethke TJ, Senger S, Stelman GJ, Toomey JR, West RI, Whittaker C, Zhou P, Young RJ. The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1588-92. Epub 2011 Feb 2. PMID:21349711 doi:10.1016/j.bmcl.2011.01.129
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Categories:
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- Coagulation factor Xa
- Homo sapiens
- Adams, C.
- Belton, D.
- Brown, D.
- Burns-Kurtis, C L.
- Chan, C.
- Chaudry, L.
- Convery, M A.
- Davies, D E.
- Exall, A M.
- Harling, J D.
- Irvine, S.
- Irving, W R.
- Kleanthous, S.
- Mclay, I M.
- Pateman, A J.
- Patikis, A N.
- Roethka, T J.
- Senger, S.
- Stelman, G J.
- Toomey, J R.
- Watson, N S.
- West, R I.
- Whittaker, C.
- Young, R J.
- Zhou, P.
- Blood clotting
- Hydrolase
- Serine protease