3hec: Difference between revisions

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Revision as of 14:39, 26 July 2012

File:3hec.png

Template:STRUCTURE 3hec

P38 in complex with Imatinib

Template:ABSTRACT PUBMED 20337484

About this Structure

3hec is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r

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