1ecc: Difference between revisions

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[[Image:1ecc.jpg|left|200px]]<br /><applet load="1ecc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ecc.jpg|left|200px]]
caption="1ecc, resolution 2.4&Aring;" />
 
'''ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH MN-CPRPP AND 5-OXO-NORLEUCINE'''<br />
{{Structure
|PDB= 1ecc |SIZE=350|CAPTION= <scene name='initialview01'>1ecc</scene>, resolution 2.4&Aring;
|SITE= <scene name='pdbsite=NTA:Ntn+Amidotransferase+Active+Site.+The+Active+Site+In+Thi+...'>NTA</scene>, <scene name='pdbsite=NTB:Ntn+Amidotransferase+Active+Site.+The+Active+Site+In+Thi+...'>NTB</scene>, <scene name='pdbsite=PRB:Phosphoribosyl+transf.+Active+Site.+The+Active+Site+In+T+...'>PRB</scene> and <scene name='pdbsite=PRT:Phosphoribosyl+transf.+Active+Site.+The+Active+Site+In+T+...'>PRT</scene>
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ONL:5-OXO-L-NORLEUCINE'>ONL</scene> and <scene name='pdbligand=PCP:1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE'>PCP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Amidophosphoribosyltransferase Amidophosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.14 2.4.2.14]
|GENE= PURF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH MN-CPRPP AND 5-OXO-NORLEUCINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ECC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=ONL:'>ONL</scene> and <scene name='pdbligand=PCP:'>PCP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Amidophosphoribosyltransferase Amidophosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.14 2.4.2.14] Known structural/functional Sites: <scene name='pdbsite=NTA:Ntn+Amidotransferase+Active+Site.+The+Active+Site+In+Thi+...'>NTA</scene>, <scene name='pdbsite=NTB:Ntn+Amidotransferase+Active+Site.+The+Active+Site+In+Thi+...'>NTB</scene>, <scene name='pdbsite=PRB:Phosphoribosyl+transf.+Active+Site.+The+Active+Site+In+T+...'>PRB</scene> and <scene name='pdbsite=PRT:Phosphoribosyl+transf.+Active+Site.+The+Active+Site+In+T+...'>PRT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECC OCA].  
1ECC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECC OCA].  


==Reference==
==Reference==
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site., Krahn JM, Kim JH, Burns MR, Parry RJ, Zalkin H, Smith JL, Biochemistry. 1997 Sep 16;36(37):11061-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9333323 9333323]
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site., Krahn JM, Kim JH, Burns MR, Parry RJ, Zalkin H, Smith JL, Biochemistry. 1997 Sep 16;36(37):11061-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9333323 9333323]
[[Category: Amidophosphoribosyltransferase]]
[[Category: Amidophosphoribosyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: transferase]]
[[Category: transferase]]


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