1ets: Difference between revisions

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[[Image:1ets.gif|left|200px]]<br /><applet load="1ets" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ets.gif|left|200px]]
caption="1ets, resolution 2.3&Aring;" />
 
'''REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS'''<br />
{{Structure
|PDB= 1ets |SIZE=350|CAPTION= <scene name='initialview01'>1ets</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GLY:GLYCINE'>GLY</scene> and <scene name='pdbligand=NAS:2-NAPHTHALENESULFONIC ACID'>NAS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ETS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=GLY:'>GLY</scene> and <scene name='pdbligand=NAS:'>NAS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETS OCA].  
1ETS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETS OCA].  


==Reference==
==Reference==
Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics., Brandstetter H, Turk D, Hoeffken HW, Grosse D, Sturzebecher J, Martin PD, Edwards BF, Bode W, J Mol Biol. 1992 Aug 20;226(4):1085-99. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1518046 1518046]
Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics., Brandstetter H, Turk D, Hoeffken HW, Grosse D, Sturzebecher J, Martin PD, Edwards BF, Bode W, J Mol Biol. 1992 Aug 20;226(4):1085-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1518046 1518046]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: hydrolase(serine proteinase)]]
[[Category: hydrolase(serine proteinase)]]


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