2w0j: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2w0j]] is a 1 chain structure | [[2w0j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0J OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 15:34, 20 October 2012
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH NSC 109555, A SPECIFIC INHIBITOR
Template:ABSTRACT PUBMED 19177354
About this Structure
2w0j is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lountos GT, Tropea JE, Zhang D, Jobson AG, Pommier Y, Shoemaker RH, Waugh DS. Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor. Protein Sci. 2009 Jan;18(1):92-100. PMID:19177354 doi:10.1002/pro.16
- Jobson AG, Cardellina JH 2nd, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R, Pommier Y. Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase. Mol Pharmacol. 2007 Oct;72(4):876-84. Epub 2007 Jul 6. PMID:17616632 doi:10.1124/mol.107.035832
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Jobson, A G.
- Lountos, G T.
- Pommier, Y.
- Shoemaker, R H.
- Tropea, J E.
- Waugh, D S.
- Zhang, D.
- Chk2 inhibitor
- Kinase
- Li-fraumeni syndrome
- Nucleotide-binding
- Oncology
- Serine/threonine-protein kinase
- Structure-assisted drug design
- Transferase
