2p4j: Difference between revisions

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==About this Structure==
==About this Structure==
[[2p4j]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4J OCA].  
[[2p4j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4J OCA].  


==See Also==
==See Also==

Revision as of 15:44, 20 October 2012

File:2p4j.png

Template:STRUCTURE 2p4j

Crystal structure of beta-secretase bond to an inhibitor with Isophthalamide Derivatives at P2-P3

Template:ABSTRACT PUBMED 17432843

About this Structure

2p4j is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni SS, Xu X, Chang W, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. J Med Chem. 2007 May 17;50(10):2399-407. Epub 2007 Apr 14. PMID:17432843 doi:10.1021/jm061338s

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