1sa5: Difference between revisions

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==About this Structure==
==About this Structure==
[[1sa5]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA5 OCA].  
[[1sa5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA5 OCA].  


==See Also==
==See Also==

Revision as of 17:13, 20 October 2012

File:1sa5.png

Template:STRUCTURE 1sa5

Rat protein farnesyltransferase complexed with FPP and BMS-214662

Template:ABSTRACT PUBMED 15170324

About this Structure

1sa5 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b

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