1fpc: Difference between revisions

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[[Image:1fpc.jpg|left|200px]]<br /><applet load="1fpc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1fpc.jpg|left|200px]]
caption="1fpc, resolution 2.3&Aring;" />
 
'''ACTIVE SITE MIMETIC INHIBITION OF THROMBIN'''<br />
{{Structure
|PDB= 1fpc |SIZE=350|CAPTION= <scene name='initialview01'>1fpc</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO3:SULFITE+ION'>SO3</scene> and <scene name='pdbligand=ANS:5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)'>ANS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''ACTIVE SITE MIMETIC INHIBITION OF THROMBIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1FPC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO3:'>SO3</scene> and <scene name='pdbligand=ANS:'>ANS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FPC OCA].  
1FPC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FPC OCA].  


==Reference==
==Reference==
Active-site mimetic inhibition of thrombin., Mathews II, Tulinsky A, Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):550-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299843 15299843]
Active-site mimetic inhibition of thrombin., Mathews II, Tulinsky A, Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):550-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299843 15299843]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]


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