1fq4: Difference between revisions

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[[Image:1fq4.jpg|left|200px]]<br /><applet load="1fq4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1fq4.jpg|left|200px]]
caption="1fq4, resolution 2.7&Aring;" />
 
'''CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A'''<br />
{{Structure
|PDB= 1fq4 |SIZE=350|CAPTION= <scene name='initialview01'>1fq4</scene>, resolution 2.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=TRM:1H-BENOXIMIDAZOLE-2-CARBOXYLIC+ACID'>TRM</scene>, <scene name='pdbligand=SMC:S-METHYLCYSTEINE'>SMC</scene>, <scene name='pdbligand=PCE:2-(3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTYL)-PENT-4-YNOIC+ACID'>PCE</scene> and <scene name='pdbligand=EMR:N-AMINOETHYLMORPHOLINE'>EMR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Saccharopepsin Saccharopepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.25 3.4.23.25]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1FQ4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=NDG:'>NDG</scene>, <scene name='pdbligand=TRM:'>TRM</scene>, <scene name='pdbligand=SMC:'>SMC</scene>, <scene name='pdbligand=PCE:'>PCE</scene> and <scene name='pdbligand=EMR:'>EMR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Saccharopepsin Saccharopepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.25 3.4.23.25] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQ4 OCA].  
1FQ4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQ4 OCA].  


==Reference==
==Reference==
X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity., Cronin NB, Badasso MO, J Tickle I, Dreyer T, Hoover DJ, Rosati RL, Humblet CC, Lunney EA, Cooper JB, J Mol Biol. 2000 Nov 10;303(5):745-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11061973 11061973]
X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity., Cronin NB, Badasso MO, J Tickle I, Dreyer T, Hoover DJ, Rosati RL, Humblet CC, Lunney EA, Cooper JB, J Mol Biol. 2000 Nov 10;303(5):745-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11061973 11061973]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharopepsin]]
[[Category: Saccharopepsin]]
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[[Category: extended beta-strand (inhibitor)]]
[[Category: extended beta-strand (inhibitor)]]


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