3nw5: Difference between revisions

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Revision as of 01:39, 27 July 2012

File:3nw5.png

Template:STRUCTURE 3nw5

Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)

Template:ABSTRACT PUBMED 20675137

About this Structure

3nw5 is a 1 chain structure of Hormone with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045

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