1fv0: Difference between revisions

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[[Image:1fv0.gif|left|200px]]<br /><applet load="1fv0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1fv0.gif|left|200px]]
caption="1fv0, resolution 1.70&Aring;" />
 
'''FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID'''<br />
{{Structure
|PDB= 1fv0 |SIZE=350|CAPTION= <scene name='initialview01'>1fv0</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=9AR:9-HYDROXY+ARISTOLOCHIC+ACID'>9AR</scene>, <scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE=
}}
 
'''FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1FV0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_pulchella Daboia russellii pulchella] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=9AR:'>9AR</scene>, <scene name='pdbligand=DIO:'>DIO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FV0 OCA].  
1FV0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_pulchella Daboia russellii pulchella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FV0 OCA].  


==Reference==
==Reference==
Structural basis of phospholipase A2 inhibition for the synthesis of prostaglandins by the plant alkaloid aristolochic acid from a 1.7 A crystal structure., Chandra V, Jasti J, Kaur P, Srinivasan A, Betzel Ch, Singh TP, Biochemistry. 2002 Sep 10;41(36):10914-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12206661 12206661]
Structural basis of phospholipase A2 inhibition for the synthesis of prostaglandins by the plant alkaloid aristolochic acid from a 1.7 A crystal structure., Chandra V, Jasti J, Kaur P, Srinivasan A, Betzel Ch, Singh TP, Biochemistry. 2002 Sep 10;41(36):10914-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12206661 12206661]
[[Category: Daboia russellii pulchella]]
[[Category: Daboia russellii pulchella]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: structure]]
[[Category: structure]]


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