1ia4: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1ia4]] is a 2 chain structure | [[1ia4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA4 OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 17:59, 20 October 2012
Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOLINEDIAMIN (GW2021)
Template:ABSTRACT PUBMED 11520201
About this Structure
1ia4 is a 2 chain structure with sequence from Candida albicans. Full crystallographic information is available from OCA.
See Also
Reference
- Whitlow M, Howard AJ, Stewart D, Hardman KD, Chan JH, Baccanari DP, Tansik RL, Hong JS, Kuyper LF. X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. J Med Chem. 2001 Aug 30;44(18):2928-32. PMID:11520201
