2b07: Difference between revisions

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Revision as of 03:30, 27 July 2012

File:2b07.png

Template:STRUCTURE 2b07

Crystal structure of PTP1B with Tricyclic Thiophene inhibitor.

Template:ABSTRACT PUBMED 16303309

About this Structure

2b07 is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Moretto AF, Kirincich SJ, Xu WX, Smith MJ, Wan ZK, Wilson DP, Follows BC, Binnun E, Joseph-McCarthy D, Foreman K, Erbe DV, Zhang YL, Tam SK, Tam SY, Lee J. Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem. 2006 Apr 1;14(7):2162-77. Epub 2005 Nov 21. PMID:16303309 doi:10.1016/j.bmc.2005.11.005
  2. Kang SA, Crane BR. Effects of interface mutations on association modes and electron-transfer rates between proteins. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15465-70. Epub 2005 Oct 14. PMID:16227441

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