1g30: Difference between revisions

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[[Image:1g30.gif|left|200px]]<br /><applet load="1g30" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1g30.gif|left|200px]]
caption="1g30, resolution 2.00&Aring;" />
 
'''THROMBIN INHIBITOR COMPLEX'''<br />
{{Structure
|PDB= 1g30 |SIZE=350|CAPTION= <scene name='initialview01'>1g30</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=T87:[(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER'>T87</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''THROMBIN INHIBITOR COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1G30 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=T87:'>T87</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G30 OCA].  
1G30 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G30 OCA].  


==Reference==
==Reference==
Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors., Nar H, Bauer M, Schmid A, Stassen JM, Wienen W, Priepke HW, Kauffmann IK, Ries UJ, Hauel NH, Structure. 2001 Jan 10;9(1):29-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11342132 11342132]
Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors., Nar H, Bauer M, Schmid A, Stassen JM, Wienen W, Priepke HW, Kauffmann IK, Ries UJ, Hauel NH, Structure. 2001 Jan 10;9(1):29-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11342132 11342132]
[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: blood coagulation cascade]]
[[Category: blood coagulation cascade]]
[[Category: factor xa]]
[[Category: factor xa]]
[[Category: inhibitor complexes]]
[[Category: inhibitor complex]]
[[Category: serine proteinase]]
[[Category: serine proteinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:45:34 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:17:28 2008''
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