1gg8: Difference between revisions

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[[Image:1gg8.gif|left|200px]]<br /><applet load="1gg8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1gg8.gif|left|200px]]
caption="1gg8, resolution 2.31&Aring;" />
 
'''DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS'''<br />
{{Structure
|PDB= 1gg8 |SIZE=350|CAPTION= <scene name='initialview01'>1gg8</scene>, resolution 2.31&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GLG:ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC+ACID+AMIDE'>GLG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene> and <scene name='pdbligand=IMP:INOSINIC ACID'>IMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1]
|GENE=
}}
 
'''DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GG8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=GLG:'>GLG</scene>, <scene name='pdbligand=PLP:'>PLP</scene> and <scene name='pdbligand=IMP:'>IMP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GG8 OCA].  
1GG8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GG8 OCA].  


==Reference==
==Reference==
Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds., Watson KA, Mitchell EP, Johnson LN, Son JC, Bichard CJ, Orchard MG, Fleet GW, Oikonomakos NG, Leonidas DD, Kontou M, et al., Biochemistry. 1994 May 17;33(19):5745-58. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8180201 8180201]
Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds., Watson KA, Mitchell EP, Johnson LN, Son JC, Bichard CJ, Orchard MG, Fleet GW, Oikonomakos NG, Leonidas DD, Kontou M, et al., Biochemistry. 1994 May 17;33(19):5745-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8180201 8180201]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: inhibitor complex]]
[[Category: inhibitor complex]]


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