1gpu: Difference between revisions

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[[Image:1gpu.gif|left|200px]]<br /><applet load="1gpu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1gpu.gif|left|200px]]
caption="1gpu, resolution 1.86&Aring;" />
 
'''TRANSKETOLASE COMPLEX WITH REACTION INTERMEDIATE'''<br />
{{Structure
|PDB= 1gpu |SIZE=350|CAPTION= <scene name='initialview01'>1gpu</scene>, resolution 1.86&Aring;
|SITE= <scene name='pdbsite=AC1:Thd+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=THD:2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE'>THD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1]
|GENE=
}}
 
'''TRANSKETOLASE COMPLEX WITH REACTION INTERMEDIATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GPU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=THD:'>THD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] Known structural/functional Site: <scene name='pdbsite=AC1:Thd+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GPU OCA].  
1GPU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GPU OCA].  


==Reference==
==Reference==
Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae., Fiedler E, Thorell S, Sandalova T, Golbik R, Konig S, Schneider G, Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):591-5. Epub 2002 Jan 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11773632 11773632]
Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae., Fiedler E, Thorell S, Sandalova T, Golbik R, Konig S, Schneider G, Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):591-5. Epub 2002 Jan 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11773632 11773632]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase(ketone residues)]]
[[Category: transferase(ketone residues)]]


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