3f3w: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3f3w]] is a 2 chain structure | [[3f3w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3W OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 20:00, 20 October 2012
Drug resistant cSrc kinase domain in complex with inhibitor RL45 (Type II)
Template:ABSTRACT PUBMED 19462975
About this Structure
3f3w is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928
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Categories:
- Pages with broken file links
- Gallus gallus
- Non-specific protein-tyrosine kinase
- Getlik, M.
- Grutter, C.
- Kluter, S.
- Rauh, D.
- Allosteric
- Atp-binding
- Dfg-out
- Drug resistance mutation
- Kinase
- Lipoprotein
- Myristate
- Nucleotide-binding
- Phosphoprotein
- Proto-oncogene
- Sh2 domain
- Sh3 domain
- Transferase
- Type ii
- Tyrosine-protein kinase