1gul: Difference between revisions

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[[Image:1gul.gif|left|200px]]<br /><applet load="1gul" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1gul.gif|left|200px]]
caption="1gul, resolution 2.70&Aring;" />
 
'''HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE'''<br />
{{Structure
|PDB= 1gul |SIZE=350|CAPTION= <scene name='initialview01'>1gul</scene>, resolution 2.70&Aring;
|SITE= <scene name='pdbsite=GTA:Glutathione+Binding+Site'>GTA</scene>, <scene name='pdbsite=GTB:Glutathione+Binding+Site'>GTB</scene>, <scene name='pdbsite=GTC:Glutathione+Binding+Site'>GTC</scene>, <scene name='pdbsite=GTD:Glutathione+Binding+Site'>GTD</scene>, <scene name='pdbsite=GTE:Glutathione+Binding+Site'>GTE</scene>, <scene name='pdbsite=GTF:Glutathione+Binding+Site'>GTF</scene>, <scene name='pdbsite=GTG:Glutathione+Binding+Site'>GTG</scene>, <scene name='pdbsite=GTH:Glutathione+Binding+Site'>GTH</scene>, <scene name='pdbsite=HTA:Electrophilic+Substrate+Binding+Site'>HTA</scene>, <scene name='pdbsite=HTB:Electrophilic+Substrate+Binding+Site'>HTB</scene>, <scene name='pdbsite=HTC:Electrophilic+Substrate+Binding+Site'>HTC</scene>, <scene name='pdbsite=HTD:Electrophilic+Substrate+Binding+Site'>HTD</scene>, <scene name='pdbsite=HTE:Electrophilic+Substrate+Binding+Site'>HTE</scene>, <scene name='pdbsite=HTF:Electrophilic+Substrate+Binding+Site'>HTF</scene>, <scene name='pdbsite=HTG:Electrophilic+Substrate+Binding+Site'>HTG</scene> and <scene name='pdbsite=HTH:Electrophilic+Substrate+Binding+Site'>HTH</scene>
|LIGAND= <scene name='pdbligand=2IB:2-IODOBENZYL GROUP'>2IB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]
|GENE=
}}
 
'''HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GUL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=2IB:'>2IB</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] Known structural/functional Sites: <scene name='pdbsite=GTA:Glutathione+Binding+Site'>GTA</scene>, <scene name='pdbsite=GTB:Glutathione+Binding+Site'>GTB</scene>, <scene name='pdbsite=GTC:Glutathione+Binding+Site'>GTC</scene>, <scene name='pdbsite=GTD:Glutathione+Binding+Site'>GTD</scene>, <scene name='pdbsite=GTE:Glutathione+Binding+Site'>GTE</scene>, <scene name='pdbsite=GTF:Glutathione+Binding+Site'>GTF</scene>, <scene name='pdbsite=GTG:Glutathione+Binding+Site'>GTG</scene>, <scene name='pdbsite=GTH:Glutathione+Binding+Site'>GTH</scene>, <scene name='pdbsite=HTA:Electrophilic+Substrate+Binding+Site'>HTA</scene>, <scene name='pdbsite=HTB:Electrophilic+Substrate+Binding+Site'>HTB</scene>, <scene name='pdbsite=HTC:Electrophilic+Substrate+Binding+Site'>HTC</scene>, <scene name='pdbsite=HTD:Electrophilic+Substrate+Binding+Site'>HTD</scene>, <scene name='pdbsite=HTE:Electrophilic+Substrate+Binding+Site'>HTE</scene>, <scene name='pdbsite=HTF:Electrophilic+Substrate+Binding+Site'>HTF</scene>, <scene name='pdbsite=HTG:Electrophilic+Substrate+Binding+Site'>HTG</scene> and <scene name='pdbsite=HTH:Electrophilic+Substrate+Binding+Site'>HTH</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUL OCA].  
1GUL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUL OCA].  


==Reference==
==Reference==
Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products., Bruns CM, Hubatsch I, Ridderstrom M, Mannervik B, Tainer JA, J Mol Biol. 1999 May 7;288(3):427-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10329152 10329152]
Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products., Bruns CM, Hubatsch I, Ridderstrom M, Mannervik B, Tainer JA, J Mol Biol. 1999 May 7;288(3):427-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10329152 10329152]
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: oxidative stress]]
[[Category: oxidative stress]]


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