1zgi: Difference between revisions

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Revision as of 09:53, 27 July 2012

File:1zgi.png

Template:STRUCTURE 1zgi

thrombin in complex with an oxazolopyridine inhibitor 21

Template:ABSTRACT PUBMED 16137886

About this Structure

1zgi is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Deng JZ, McMasters DR, Rabbat PM, Williams PD, Coburn CA, Yan Y, Kuo LC, Lewis SD, Lucas BJ, Krueger JA, Strulovici B, Vacca JP, Lyle TA, Burgey CS. Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4411-6. PMID:16137886 doi:https://dx.doi.org/10.1016/j.bmcl.2005.07.022

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