2ant: Difference between revisions

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==About this Structure==
==About this Structure==
[[2ant]] is a 2 chain structure of [[Antithrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANT OCA].  
[[2ant]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANT OCA].  


==See Also==
==See Also==

Revision as of 20:25, 20 October 2012

File:2ant.png

Template:STRUCTURE 2ant

THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE

Template:ABSTRACT PUBMED 9067613

About this Structure

2ant is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Skinner R, Abrahams JP, Whisstock JC, Lesk AM, Carrell RW, Wardell MR. The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J Mol Biol. 1997 Feb 28;266(3):601-9. PMID:9067613 doi:10.1006/jmbi.1996.0798
  2. Alberdi E, Hyde CC, Becerra SP. Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. Biochemistry. 1998 Jul 28;37(30):10643-52. PMID:9692954 doi:10.1021/bi9802317
  3. Whisstock JC, Pike RN, Jin L, Skinner R, Pei XY, Carrell RW, Lesk AM. Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparindagger. J Mol Biol. 2000 Sep 1;301(5):1287-305. PMID:10966821 doi:10.1006/jmbi.2000.3982

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