1gz3: Difference between revisions

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[[Image:1gz3.jpg|left|200px]]<br /><applet load="1gz3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1gz3.jpg|left|200px]]
caption="1gz3, resolution 2.3&Aring;" />
 
'''MOLECULAR MECHANISM FOR THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE'''<br />
{{Structure
|PDB= 1gz3 |SIZE=350|CAPTION= <scene name='initialview01'>1gz3</scene>, resolution 2.3&Aring;
|SITE= <scene name='pdbsite=AC1:Fum+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene> and <scene name='pdbligand=FUM:FUMARIC ACID'>FUM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Malate_dehydrogenase_(oxaloacetate-decarboxylating) Malate dehydrogenase (oxaloacetate-decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.38 1.1.1.38]
|GENE=
}}
 
'''MOLECULAR MECHANISM FOR THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GZ3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=OXL:'>OXL</scene>, <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=ATP:'>ATP</scene> and <scene name='pdbligand=FUM:'>FUM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Malate_dehydrogenase_(oxaloacetate-decarboxylating) Malate dehydrogenase (oxaloacetate-decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.38 1.1.1.38] Known structural/functional Site: <scene name='pdbsite=AC1:Fum+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GZ3 OCA].  
1GZ3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GZ3 OCA].  


==Reference==
==Reference==
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate., Yang Z, Lanks CW, Tong L, Structure. 2002 Jul;10(7):951-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12121650 12121650]
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate., Yang Z, Lanks CW, Tong L, Structure. 2002 Jul;10(7):951-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12121650 12121650]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Malate dehydrogenase (oxaloacetate-decarboxylating)]]
[[Category: Malate dehydrogenase (oxaloacetate-decarboxylating)]]
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[[Category: allosteric regulation]]
[[Category: allosteric regulation]]
[[Category: energy metabolism]]
[[Category: energy metabolism]]
[[Category: kinetics]]
[[Category: kinetic]]
[[Category: mitochondrion.]]
[[Category: mitochondrion.]]
[[Category: nad]]
[[Category: nad]]
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[[Category: protein structure]]
[[Category: protein structure]]


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