1xkk: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1xkk]] is a 1 chain structure | [[1xkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKK OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 20:33, 20 October 2012
EGFR kinase domain complexed with a quinazoline inhibitor- GW572016
Template:ABSTRACT PUBMED 15374980
About this Structure
1xkk is a 1 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L. A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res. 2004 Sep 15;64(18):6652-9. PMID:15374980 doi:10.1158/0008-5472.CAN-04-1168
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Epidermal Growth Factor Receptor
- Homo sapiens
- RCSB PDB Molecule of the Month
- Transferase
- Alligood, K J.
- Dickerson, S H.
- Ellis, B.
- Gilmer, T M.
- Hassell, A.
- Horne, E.
- Lackey, K.
- McDonald, O B.
- Pennisi, C.
- Rusnak, D W.
- Shewchuk, L M.
- Truesdale, A T.
- Wood, E R.
- Yuan, D.
- Egfr
- Epidermal growth factor receptor
- Kinase