1h16: Difference between revisions

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[[Image:1h16.gif|left|200px]]<br /><applet load="1h16" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1h16.gif|left|200px]]
caption="1h16, resolution 1.53&Aring;" />
 
'''PYRUVATE FORMATE-LYASE (E.COLI) IN COMPLEX WITH PYRUVATE AND COA'''<br />
{{Structure
|PDB= 1h16 |SIZE=350|CAPTION= <scene name='initialview01'>1h16</scene>, resolution 1.53&Aring;
|SITE= <scene name='pdbsite=PYR:Coa+Binding+Site+For+Chain+A'>PYR</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=DTL:D-TREITOL'>DTL</scene> and <scene name='pdbligand=PG4:TETRAETHYLENE GLYCOL'>PG4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Formate_C-acetyltransferase Formate C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.54 2.3.1.54]
|GENE=
}}
 
'''PYRUVATE FORMATE-LYASE (E.COLI) IN COMPLEX WITH PYRUVATE AND COA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1H16 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=COA:'>COA</scene>, <scene name='pdbligand=PYR:'>PYR</scene>, <scene name='pdbligand=DTL:'>DTL</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Formate_C-acetyltransferase Formate C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.54 2.3.1.54] Known structural/functional Site: <scene name='pdbsite=PYR:Coa+Binding+Site+For+Chain+A'>PYR</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H16 OCA].  
1H16 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H16 OCA].  


==Reference==
==Reference==
X-ray structure of pyruvate formate-lyase in complex with pyruvate and CoA. How the enzyme uses the Cys-418 thiyl radical for pyruvate cleavage., Becker A, Kabsch W, J Biol Chem. 2002 Oct 18;277(42):40036-42. Epub 2002 Aug 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12163496 12163496]
X-ray structure of pyruvate formate-lyase in complex with pyruvate and CoA. How the enzyme uses the Cys-418 thiyl radical for pyruvate cleavage., Becker A, Kabsch W, J Biol Chem. 2002 Oct 18;277(42):40036-42. Epub 2002 Aug 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12163496 12163496]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Formate C-acetyltransferase]]
[[Category: Formate C-acetyltransferase]]
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[[Category: transferase]]
[[Category: transferase]]


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