1h9m: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1h9m.jpg|left|200px]]<br /><applet load="1h9m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1h9m.jpg|left|200px]]
caption="1h9m, resolution 1.65&Aring;" />
 
'''TWO CRYSTAL STRUCTURES OF THE CYTOPLASMIC MOLYBDATE-BINDING PROTEIN MODG SUGGEST A NOVEL COOPERATIVE BINDING MECHANISM AND PROVIDE INSIGHTS INTO LIGAND-BINDING SPECIFICITY. PEG-GROWN FORM WITH MOLYBDATE BOUND'''<br />
{{Structure
|PDB= 1h9m |SIZE=350|CAPTION= <scene name='initialview01'>1h9m</scene>, resolution 1.65&Aring;
|SITE= <scene name='pdbsite=AC1:Moo+Binding+Site+For+Chain+A1142+Symmetry+Related+Subuni+...'>AC1</scene>, <scene name='pdbsite=AC2:Moo+Binding+Site+For+Chain+A1143+Symmetry+Related+Subuni+...'>AC2</scene>, <scene name='pdbsite=AC3:Moo+Binding+Site+For+Chain+A1144+Symmetry+Related+Subuni+...'>AC3</scene>, <scene name='pdbsite=AC4:Moo+Binding+Site+For+Chain+A1145+Symmetry+Related+Subuni+...'>AC4</scene>, <scene name='pdbsite=AC5:Moo+Binding+Site+For+Chain+B1142+Symmetry+Related+Subuni+...'>AC5</scene>, <scene name='pdbsite=AC6:Moo+Binding+Site+For+Chain+B1143+Symmetry+Related+Subuni+...'>AC6</scene>, <scene name='pdbsite=AC7:Moo+Binding+Site+For+Chain+B1144+Symmetry+Related+Subuni+...'>AC7</scene> and <scene name='pdbsite=AC8:Moo+Binding+Site+For+Chain+B1145+Symmetry+Related+Subuni+...'>AC8</scene>
|LIGAND= <scene name='pdbligand=MOO:MOLYBDATE ION'>MOO</scene>
|ACTIVITY=
|GENE= MODG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 Azotobacter vinelandii])
}}
 
'''TWO CRYSTAL STRUCTURES OF THE CYTOPLASMIC MOLYBDATE-BINDING PROTEIN MODG SUGGEST A NOVEL COOPERATIVE BINDING MECHANISM AND PROVIDE INSIGHTS INTO LIGAND-BINDING SPECIFICITY. PEG-GROWN FORM WITH MOLYBDATE BOUND'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1H9M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii] with <scene name='pdbligand=MOO:'>MOO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Moo+Binding+Site+For+Chain+A1142+Symmetry+Related+Subuni+...'>AC1</scene>, <scene name='pdbsite=AC2:Moo+Binding+Site+For+Chain+A1143+Symmetry+Related+Subuni+...'>AC2</scene>, <scene name='pdbsite=AC3:Moo+Binding+Site+For+Chain+A1144+Symmetry+Related+Subuni+...'>AC3</scene>, <scene name='pdbsite=AC4:Moo+Binding+Site+For+Chain+A1145+Symmetry+Related+Subuni+...'>AC4</scene>, <scene name='pdbsite=AC5:Moo+Binding+Site+For+Chain+B1142+Symmetry+Related+Subuni+...'>AC5</scene>, <scene name='pdbsite=AC6:Moo+Binding+Site+For+Chain+B1143+Symmetry+Related+Subuni+...'>AC6</scene>, <scene name='pdbsite=AC7:Moo+Binding+Site+For+Chain+B1144+Symmetry+Related+Subuni+...'>AC7</scene> and <scene name='pdbsite=AC8:Moo+Binding+Site+For+Chain+B1145+Symmetry+Related+Subuni+...'>AC8</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9M OCA].  
1H9M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9M OCA].  


==Reference==
==Reference==
Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity., Delarbre L, Stevenson CE, White DJ, Mitchenall LA, Pau RN, Lawson DM, J Mol Biol. 2001 May 18;308(5):1063-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11352591 11352591]
Two crystal structures of the cytoplasmic molybdate-binding protein ModG suggest a novel cooperative binding mechanism and provide insights into ligand-binding specificity., Delarbre L, Stevenson CE, White DJ, Mitchenall LA, Pau RN, Lawson DM, J Mol Biol. 2001 May 18;308(5):1063-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11352591 11352591]
[[Category: Azotobacter vinelandii]]
[[Category: Azotobacter vinelandii]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 23: Line 32:
[[Category: molybdate homeostasis]]
[[Category: molybdate homeostasis]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:59:01 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:34:08 2008''