3h5s: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3h5s]] is a 2 chain structure | [[3h5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5S OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 21:56, 20 October 2012
Hepatitis C virus polymerase NS5B with saccharin inhibitor
Template:ABSTRACT PUBMED 19709881
About this Structure
3h5s is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Adjabeng G, Elworthy TR, Li J, Wang B, Bamberg JT, Harris SF, Wong A, Leveque VJ, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Larrabee S, Brandl M, Briggs A, Sukhtankar S, Farrell R. Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5652-6. Epub 2009 Aug 8. PMID:19709881 doi:10.1016/j.bmcl.2009.08.022
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Categories:
- Pages with broken file links
- Hepatitis c virus
- RNA-directed RNA polymerase
- Harris, S F.
- Wong, A.
- Apoptosis
- Atp-binding
- Capsid protein
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Envelope protein
- Fusion protein
- Glycoprotein
- Hcv
- Helicase
- Hepatitis
- Host-virus interaction
- Hydrolase
- Interferon antiviral system evasion
- Lipid droplet
- Lipoprotein
- Membrane
- Metal-binding
- Mitochondrion
- Multifunctional enzyme
- Ns5b
- Nucleotide-binding
- Nucleotidyltransferase
- Nucleus
- Oncogene
- Palmitate
- Phosphoprotein
- Protease
- Ribonucleoprotein
- Rna replication
- Rna-binding
- Rna-directed rna polymerase
- Secreted
- Serine protease
- Sh3-binding
- Thiol protease
- Transcription
- Transcription regulation
- Transferase
- Transferase rna-dependent rna polymerase
- Transmembrane
- Viral nucleoprotein
- Virion
