1hk8: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1hk8.gif|left|200px]]<br /><applet load="1hk8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1hk8.gif|left|200px]]
caption="1hk8, resolution 2.45&Aring;" />
 
'''STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP'''<br />
{{Structure
|PDB= 1hk8 |SIZE=350|CAPTION= <scene name='initialview01'>1hk8</scene>, resolution 2.45&Aring;
|SITE= <scene name='pdbsite=DG1:Zn2++Binding+Site+For+Chain+A'>DG1</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=DGT:2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE'>DGT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonucleoside-triphosphate_reductase Ribonucleoside-triphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.2 1.17.4.2]
|GENE=
}}
 
'''STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1HK8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t2 Enterobacteria phage t2] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=DGT:'>DGT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1H77. Active as [http://en.wikipedia.org/wiki/Ribonucleoside-triphosphate_reductase Ribonucleoside-triphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.2 1.17.4.2] Known structural/functional Site: <scene name='pdbsite=DG1:Zn2++Binding+Site+For+Chain+A'>DG1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK8 OCA].  
1HK8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t2 Enterobacteria phage t2]. This structure supersedes the now removed PDB entry 1H77. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK8 OCA].  


==Reference==
==Reference==
A metal-binding site in the catalytic subunit of anaerobic ribonucleotide reductase., Logan DT, Mulliez E, Larsson KM, Bodevin S, Atta M, Garnaud PE, Sjoberg BM, Fontecave M, Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3826-31. Epub 2003 Mar 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12655046 12655046]
A metal-binding site in the catalytic subunit of anaerobic ribonucleotide reductase., Logan DT, Mulliez E, Larsson KM, Bodevin S, Atta M, Garnaud PE, Sjoberg BM, Fontecave M, Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3826-31. Epub 2003 Mar 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12655046 12655046]
[[Category: Enterobacteria phage t2]]
[[Category: Enterobacteria phage t2]]
[[Category: Ribonucleoside-triphosphate reductase]]
[[Category: Ribonucleoside-triphosphate reductase]]
Line 27: Line 36:
[[Category: substrate specificity]]
[[Category: substrate specificity]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:02:07 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:38:11 2008''
Retrieved from "https://proteopedia.org/1hk8"