1hnn: Difference between revisions

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[[Image:1hnn.jpg|left|200px]]<br /><applet load="1hnn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1hnn.jpg|left|200px]]
caption="1hnn, resolution 2.40&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)'''<br />
{{Structure
|PDB= 1hnn |SIZE=350|CAPTION= <scene name='initialview01'>1hnn</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=SKF:1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE'>SKF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28]
|GENE= PNMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1HNN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SAH:'>SAH</scene> and <scene name='pdbligand=SKF:'>SKF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNN OCA].  
1HNN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNN OCA].  


==Reference==
==Reference==
Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT., Martin JL, Begun J, McLeish MJ, Caine JM, Grunewald GL, Structure. 2001 Oct;9(10):977-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11591352 11591352]
Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT., Martin JL, Begun J, McLeish MJ, Caine JM, Grunewald GL, Structure. 2001 Oct;9(10):977-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11591352 11591352]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]
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[[Category: s-adenosyl methionine]]
[[Category: s-adenosyl methionine]]


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