1hwr: Difference between revisions

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[[Image:1hwr.gif|left|200px]]<br /><applet load="1hwr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1hwr.gif|left|200px]]
caption="1hwr, resolution 1.80&Aring;" />
 
'''MOLECULAR RECOGNITION OF CYCLIC UREA HIV PROTEASE INHIBITORS'''<br />
{{Structure
|PDB= 1hwr |SIZE=350|CAPTION= <scene name='initialview01'>1hwr</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=216:[4-R-(4-ALPHA,6-BETA,7-BETA]-HEXAHYDRO-5,6-DI(HYDROXY)-1,3-DI(ALLYL)-4,7-BISPHENYLMETHYL)-2H-1,3-DIAZEPINONE'>216</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE=
}}
 
'''MOLECULAR RECOGNITION OF CYCLIC UREA HIV PROTEASE INHIBITORS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1HWR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=216:'>216</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWR OCA].  
1HWR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HWR OCA].  


==Reference==
==Reference==
Molecular recognition of cyclic urea HIV-1 protease inhibitors., Ala PJ, DeLoskey RJ, Huston EE, Jadhav PK, Lam PY, Eyermann CJ, Hodge CN, Schadt MC, Lewandowski FA, Weber PC, McCabe DD, Duke JL, Chang CH, J Biol Chem. 1998 May 15;273(20):12325-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9575185 9575185]
Molecular recognition of cyclic urea HIV-1 protease inhibitors., Ala PJ, DeLoskey RJ, Huston EE, Jadhav PK, Lam PY, Eyermann CJ, Hodge CN, Schadt MC, Lewandowski FA, Weber PC, McCabe DD, Duke JL, Chang CH, J Biol Chem. 1998 May 15;273(20):12325-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9575185 9575185]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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