1hyv: Difference between revisions

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[[Image:1hyv.gif|left|200px]]<br /><applet load="1hyv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1hyv.gif|left|200px]]
caption="1hyv, resolution 1.7&Aring;" />
 
'''HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM'''<br />
{{Structure
|PDB= 1hyv |SIZE=350|CAPTION= <scene name='initialview01'>1hyv</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=TTA:TETRAPHENYL-ARSONIUM'>TTA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE=
}}
 
'''HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1HYV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=TTA:'>TTA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYV OCA].  
1HYV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYV OCA].  


==Reference==
==Reference==
Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain., Molteni V, Greenwald J, Rhodes D, Hwang Y, Kwiatkowski W, Bushman FD, Siegel JS, Choe S, Acta Crystallogr D Biol Crystallogr. 2001 Apr;57(Pt 4):536-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11264582 11264582]
Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain., Molteni V, Greenwald J, Rhodes D, Hwang Y, Kwiatkowski W, Bushman FD, Siegel JS, Choe S, Acta Crystallogr D Biol Crystallogr. 2001 Apr;57(Pt 4):536-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11264582 11264582]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: dna integration]]
[[Category: dna integration]]


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